Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953447 | 0.81 | HTT (0.50) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL14033785 | 0.79 | MAPT (0.53) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL4912957 | 0.79 | MAPT (0.53) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL3566913 | 0.76 | PIK3C3 (0.35) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL504041 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL12778132 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL504040 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL13503036 | 0.74 | MAPT (0.47) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL3605170 | 0.74 | MAPT (0.47) | ALDH1A1GAAKDM4EMAPTHTT | |
| SCHEMBL17451268 | 0.74 | LMNA (0.31) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4683628-A2 | CDK2 MODULATORS, COMPOSITIONS, AND METHODS OF USE THEREOF | Type6 Therapeutics, Inc. (US) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024196961-A2 | CDK2 MODULATORS, COMPOSITIONS, AND METHODS OF USE THEREOF | TYPE6 THERAPEUTICS, INC. (US) | 2024-09-26 | — | — | WO | disclosed |