Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 20/20 | 0.79 |
| ▸ | MAT1A | Q00266 | 1/20 | 0.79 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31145444 | 1.00 | MAT2A (0.79) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL22103463 | 1.00 | MAT2A (0.79) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL22093063 | 1.00 | MAT2A (0.79) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL29571405 | 1.00 | MAT2A (0.79) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL22093477 | 1.00 | MAT2A (0.79) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL22094104 | 0.91 | MAT2A (0.71) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL29570392 | 0.91 | MAT2A (0.71) | MAT2AMAT1APRMT5CYP1A2 | |
| SCHEMBL22093249 | 0.88 | MAT2A (1.00) | MAT2AMAT1APRMT5 | |
| SCHEMBL22093247 | 0.88 | MAT2A (1.00) | MAT2AMAT1APRMT5 | |
| SCHEMBL29569856 | 0.88 | MAT2A (1.00) | MAT2AMAT1APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |