SCHEMBL31145387

SCHEMBL31145387

CNc1nc(=O)n(-c2cccnc2C(F)(F)F)c2cc(C(F)(F)F)cc(F)c12

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAT2A P31153 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22093459 1.00 MAT2A (0.52) MAT2A
SCHEMBL29570844 0.87 MAT2A (0.49) MAT2A
SCHEMBL22093344 0.87 MAT2A (0.49) MAT2A
SCHEMBL22093749 0.84 MAT2A (0.44) MAT2A
SCHEMBL31145505 0.84 MAT2A (0.44) MAT2A
SCHEMBL22094007 0.84 MAT2A (0.40) MAT2A
SCHEMBL29570916 0.84 MAT2A (0.40) MAT2A
SCHEMBL29570176 0.83 MAT2A (0.74) MAT2A
SCHEMBL22093730 0.83 MAT2A (0.74) MAT2A
SCHEMBL31145477 0.81 MAT2A (0.59) MAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528824-A 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2025-02-28 — — CN disclosed
CN-113166078-B 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2024-11-19 — — CN disclosed
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