SCHEMBL31145433

SCHEMBL31145433

CNc1nc(=O)n(-c2ccccc2Cl)c2cc(Cl)cc(F)c12

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAT2A P31153 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22093169 1.00 MAT2A (0.56) MAT2A
SCHEMBL29571368 0.86 MAT2A (0.67) MAT2A
SCHEMBL22093363 0.86 MAT2A (0.67) MAT2A
SCHEMBL22103265 0.84 MAT2A (0.59) MAT2A
SCHEMBL29570930 0.84 MAT2A (0.59) MAT2A
SCHEMBL31145456 0.84 MAT2A (0.46) MAT2A
SCHEMBL22093112 0.84 MAT2A (0.46) MAT2A
SCHEMBL23734084 0.80 MAT2A (0.57) MAT2A
SCHEMBL22093348 0.80 MAT2A (0.73) MAT2A
SCHEMBL29569769 0.80 MAT2A (0.73) MAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528824-A 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2025-02-28 — — CN disclosed
CN-113166078-B 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2024-11-19 — — CN disclosed
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