Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458519 | 0.86 | MAPT (0.57) | KIF11MAPTCA12CA9KDM4E | |
| SCHEMBL13244957 | 0.86 | KIF11 (0.54) | KIF11MAPTCA12CA9KDM4E | |
| SCHEMBL8873312 | 0.74 | MAPT (0.58) | KIF11MAPTCA12CA9JUN | |
| SCHEMBL3642521 | 0.73 | DAO (0.60) | CA12CA9KDM4EPARP1ALDH1A1 | |
| SCHEMBL30014154 | 0.73 | KDM4E (0.53) | KIF11MAPTCA12CA9KDM4E | |
| SCHEMBL184315 | 0.73 | KDM4E (0.53) | KIF11MAPTCA12CA9KDM4E | |
| SCHEMBL2054576 | 0.72 | KIF11 (0.54) | KIF11CA12CA9KDM4EPARP1 | |
| SCHEMBL21248093 | 0.72 | KDM4E (0.58) | KIF11MAPTCA12CA9KDM4E | |
| SCHEMBL7040910 | 0.72 | KIF11 (0.58) | KIF11MAPTCA12CA9KDM4E | |
| SCHEMBL7033184 | 0.72 | KIF11 (0.58) | KIF11CA12CA9KDM4EPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |