SCHEMBL31145648

SCHEMBL31145648

CCc1ccc2c(NC)nc(=O)n(-c3ccccc3)c2c1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAT2A P31153 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22093182 1.00 MAT2A (0.70) MAT2A
SCHEMBL22103432 0.90 MAT2A (0.67) MAT2A
SCHEMBL22103548 0.89 MAT2A (0.68) MAT2A
SCHEMBL22103286 0.84 MAT2A (0.52) MAT2A
SCHEMBL22103279 0.83 MAT2A (0.56) MAT2A
SCHEMBL22093819 0.83 MAT2A (0.74) MAT2A
SCHEMBL29569929 0.83 MAT2A (0.74) MAT2A
SCHEMBL22093154 0.82 MAT2A (0.73) MAT2A
SCHEMBL22093415 0.82 MAT2A (1.00) MAT2A
SCHEMBL22093208 0.82 MAT2A (0.79) MAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528824-A 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2025-02-28 — — CN disclosed
CN-113166078-B 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2024-11-19 — — CN disclosed
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