Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146206 | 1.00 | P2RX7 (0.31) | P2RX7NPC1 | |
| SCHEMBL31146194 | 1.00 | P2RX7 (0.31) | P2RX7NPC1 | |
| SCHEMBL31146105 | 0.93 | NPC1 (0.31) | NPC1 | |
| SCHEMBL31146026 | 0.93 | NPC1 (0.31) | NPC1 | |
| SCHEMBL31145836 | 0.88 | NPC1 (0.33) | NPC1 | |
| SCHEMBL31146034 | 0.88 | NPC1 (0.33) | NPC1 | |
| SCHEMBL31146178 | 0.80 | NPC1 (0.37) | P2RX7NPC1 | |
| SCHEMBL31146108 | 0.80 | NPC1 (0.38) | NPC1 | |
| SCHEMBL31145884 | 0.70 | RPS6KB1 (0.31) | — | |
| SCHEMBL31145985 | 0.69 | NPC1 (0.39) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688748-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206339-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |