Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178075 | 0.86 | JAK1 (0.37) | ADORA1PDGFRBKDRJAK1MAPT | |
| SCHEMBL3801893 | 0.84 | ADORA1 (0.44) | MEN1KMT2AADORA1PDGFRBKDR | |
| SCHEMBL13663989 | 0.80 | ADORA1 (0.43) | ADORA1JAK1HSD17B10ALDH1A1ADORA2A | |
| SCHEMBL9451618 | 0.77 | ADORA2A (0.37) | ADORA1PDGFRBKDRJAK1KDM4E | |
| SCHEMBL27176130 | 0.76 | MEN1 (0.43) | MEN1KMT2AADORA1PDGFRBKDR | |
| SCHEMBL30083280 | 0.76 | MEN1 (0.43) | MEN1KMT2AADORA1PDGFRBKDR | |
| SCHEMBL16743055 | 0.75 | TYRO3 (0.40) | ADORA1KDRADORA2A | |
| SCHEMBL10652298 | 0.74 | JAK2 (0.46) | ADORA1POLBL3MBTL1JAK1ALDH1A1 | |
| SCHEMBL22476359 | 0.74 | ADORA1 (0.56) | MEN1KMT2AADORA1PDGFRBKDR | |
| SCHEMBL8907430 | 0.74 | AXL (0.34) | ADORA1KDRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229281-A | Di-parallel ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023168830-A1 | HEMTAC SMALL MOLECULE DEGRADATION AGENT AND USE THEREOF | 山东大学 | 2023-09-14 | — | — | WO | disclosed |
| EP-3515923-A1 | PRODRUGS OF FLUORINATED ACYCLIC NUCLEOSIDE PHOSPHONATES | Katholieke Universiteit Leuven (BE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018055071-A1 | PRODRUGS OF FLUORINATED ACYCLIC NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018055071-A1 | PRODRUGS OF FLUORINATED ACYCLIC NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-03-29 | — | — | WO | disclosed |
| US-9862983-B1 | Recombinase-based amplification with substitute nucleotides | BENNER STEVEN (US) | 2018-01-09 | — | — | US | disclosed |
| US-9637783-B1 | Amplification of oligonucleotides containing non-standard nucleotides by polymerase chain reactions | DEFENSE THREAT REDUCTION AGENCY; DEPT. OF DEFENSE, UNITED STATES GOVERNMENT | 2017-05-02 | — | — | US | disclosed |
| CN-102971335-B | Reversibly terminating primer extension reagents | 史蒂芬·阿尔伯特·本纳 | 2016-06-29 | — | — | CN | disclosed |
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |
| CN-102971335-A | Reversibly terminating primer extension reagents | BENNER STEVEN ALBERT | 2013-03-13 | — | — | CN | disclosed |
| EP-1869027-A2 | ALKYNYL PYRROLOPYRIMIDINES AND RELATED ANALOGS AS HSP90-INHIBITORS | Conforma Therapeutics Corporation (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20070173483-A1 | Pyrrolopyrimidines and Related Analogs as HSP90-Inhibitors | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-07-26 | — | — | US | disclosed |
| US-7138402-B2 | Pyrrolopyrimidines and related analogs as HSP90-inhibitors | CONFORMA THERAPEUTICS CORPORATION (US) | 2006-11-21 | — | — | US | disclosed |
| US-20060223797-A1 | ALKYNYL PYRROLOPYRIMIDINES AND RELATED ANALOGS AS HSP90-INHIBITORS | CONFORMA THERAPEUTICS CORPORATION | 2006-10-05 | — | — | US | disclosed |
| WO-2006105372-A2 | ALKYNYL PYRROLOPYRIMIDINES AND RELATED ANALOGS AS HSP90-INHIBITORS | CONFORMA THERAPEUTICS CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-1670802-A2 | NOVEL HETEROCYCLIC COMPOUNDS AS HSP90-INHIBITORS | Conforma Therapeutic Corporation (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050107343-A1 | Pyrrolopyrimidines and related analogs as HSP90-inhibitors | CONFORMA THERAPEUTICS CORPORATION | 2005-05-19 | — | — | US | disclosed |
| WO-2005028434-A2 | NOVEL HETEROCYCLIC COMPOUNDS AS HSP90-INHIBITORS | CONFORMA THERAPEUTICS CORPORATION (US) | 2005-03-31 | — | — | WO | disclosed |
| US-6093807-A | Sugar-modified 7-deaza-7-substituted oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0567223-A1 | Glutamic acid derivatives as antineoplastic agents | ELI LILLY AND COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107343-A1 | Pyrrolopyrimidines and related analogs as HSP90-inhibitors | HSP90AB2P, HSP90AB1, HSP90AA1 | MEN1 4106/4885KMT2A 3946/4885ADORA1 4814/4885 |
| US-20060223797-A1 | ALKYNYL PYRROLOPYRIMIDINES AND RELATED ANALOGS AS HSP90-INHIBITORS | HSP90AB2P, HSP90AB1, HSP90AA1 | MEN1 4789/4885KMT2A 4204/4885ADORA1 4689/4885 |
| US-20070173483-A1 | Pyrrolopyrimidines and Related Analogs as HSP90-Inhibitors | HSP90AB2P, HSP90AB1, HSP90AA1 | MEN1 4106/4885KMT2A 3946/4885ADORA1 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.