Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146776 | 0.83 | FGFR1 (0.53) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL29449407 | 0.80 | MEN1 (0.50) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL26556567 | 0.79 | MEN1 (0.53) | MEN1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL38658797 | 0.78 | MEN1 (0.57) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL28580109 | 0.77 | MEN1 (0.60) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL20735101 | 0.76 | MEN1 (0.62) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL18566555 | 0.75 | MEN1 (0.58) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL12495525 | 0.75 | MEN1 (0.56) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL31146821 | 0.75 | RXFP1 (0.47) | FGFR1KDRPDGFRAMEN1KMT2A | |
| SCHEMBL12494779 | 0.74 | MEN1 (0.60) | FGFR1KDRPDGFRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724811-A | Preparation method and application of aldehyde group-containing substituted naphthalimide derivative | 中国医学科学院药物研究所 | 2024-10-01 | — | — | CN | disclosed |