Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30436778 | 0.87 | TERT (0.55) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL25420764 | 0.87 | TERT (0.55) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL29449407 | 0.84 | MEN1 (0.50) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL17185506 | 0.80 | MAPT (0.54) | MEN1KMT2ARAB9AL3MBTL1CYP1B1 | |
| SCHEMBL31146744 | 0.79 | FGFR1 (0.48) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL8400470 | 0.78 | GRM5 (0.43) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL30436709 | 0.77 | HEXA (0.46) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL25417476 | 0.77 | HEXA (0.46) | MEN1KMT2ARAB9AMAPK1L3MBTL1 | |
| SCHEMBL18069192 | 0.76 | KMT2A (0.46) | MEN1KMT2AL3MBTL1MAPTPOLB | |
| SCHEMBL12495525 | 0.76 | MEN1 (0.56) | MEN1KMT2ARAB9AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | PSEN1, PSEN2, MAPT | MEN1 521/4885KMT2A 4003/4885RAB9A 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.