Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | Q9HBH1 | 2/20 | 0.34 | |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289317 | 0.76 | MAOA (0.33) | MEN1KMT2ASMN1; SMN2MAPTBCHE | |
| SCHEMBL31151816 | 0.76 | MAOA (0.39) | MEN1KMT2ANOX1SMN1; SMN2GSK3B | |
| SCHEMBL27516784 | 0.74 | MAOA (0.41) | NOX1SMN1; SMN2GSK3BBCHE | |
| SCHEMBL28820660 | 0.72 | BCHE (0.39) | MAPTBCHELMNAPOLB | |
| SCHEMBL28820816 | 0.72 | BCHE (0.39) | MAPTBCHELMNAPOLB | |
| SCHEMBL29815013 | 0.70 | APP (0.35) | KMT2ASMN1; SMN2MAPTBCHE | |
| SCHEMBL30846519 | 0.70 | GSK3B (0.42) | MEN1KMT2ANOX1SMN1; SMN2GSK3B | |
| SCHEMBL27987207 | 0.70 | MAOA (0.39) | MEN1KMT2ANOX1SMN1; SMN2GSK3B | |
| SCHEMBL27870759 | 0.70 | MAOA (0.39) | SMN1; SMN2GSK3BMAPT | |
| SCHEMBL31231823 | 0.69 | TP53 (0.39) | MEN1KMT2ANOX1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702692-A | Preparation method of benzothiazole tetrafluoroborate fluorescent dye | 苏州络森生物科技有限公司 | 2024-09-27 | — | — | CN | disclosed |