Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31148231 | 1.00 | RAB9A (0.54) | RAB9ANPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30129949 | 0.83 | MEN1 (0.52) | NPC1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL31148125 | 0.83 | MEN1 (0.52) | NPC1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL30945061 | 0.83 | HDAC8 (0.51) | NPC1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL31148039 | 0.81 | NPC1 (0.51) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL31148023 | 0.81 | NPC1 (0.51) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL31148213 | 0.80 | NPC1 (0.48) | NPC1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL31148130 | 0.78 | NPC1 (0.45) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL13125283 | 0.78 | HDAC8 (0.43) | NPC1ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL13149992 | 0.78 | HDAC8 (0.43) | NPC1ALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695236-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024216094-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |