Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23143261 | 1.00 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2566232 | 0.88 | KDM4E (0.42) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11358297 | 0.88 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21128314 | 0.87 | ALDH1A1 (0.42) | TSHRALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL1475885 | 0.84 | TSHR (0.41) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23143266 | 0.83 | ELANE (0.42) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30753543 | 0.83 | ELANE (0.42) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30421542 | 0.83 | KMT2A (0.42) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1669584 | 0.83 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29906642 | 0.83 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118748995-A | 5-Pyrimidine carboxamide derivatives and methods of use thereof | 亚根达医疗公司 | 2024-10-08 | — | — | CN | disclosed |