Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645973 | 0.92 | TP53 (0.46) | RXFP1TP53THRBMAPTPOLB | |
| SCHEMBL31150031 | 0.86 | MAPT (0.48) | RXFP1TP53THRBABCG2MAPT | |
| SCHEMBL31149864 | 0.86 | MAPT (0.44) | RXFP1TP53THRBMAPTPOLB | |
| SCHEMBL31149972 | 0.86 | MAPT (0.54) | RXFP1TP53THRBABCG2MAPT | |
| SCHEMBL31150092 | 0.83 | TP53 (0.51) | RXFP1TP53THRBABCG2MAPT | |
| SCHEMBL29645516 | 0.82 | MAPT (0.46) | TP53THRBMAPTPOLBSMN1; SMN2 | |
| SCHEMBL31149944 | 0.82 | RXFP1 (0.47) | RXFP1TP53THRBMAPTPOLB | |
| SCHEMBL31149929 | 0.81 | THRB (0.43) | RXFP1TP53THRBMAPTPOLB | |
| SCHEMBL31150038 | 0.81 | MAPT (0.56) | RXFP1TP53THRBMAPTPOLB | |
| SCHEMBL31150082 | 0.80 | MAPT (0.43) | TP53THRBMAPTPOLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |