Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31151955 | 1.00 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151972 | 0.88 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151962 | 0.88 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151968 | 0.86 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151891 | 0.86 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151976 | 0.84 | CRBN (0.41) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151921 | 0.84 | CRBN (0.41) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151932 | 0.81 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151991 | 0.81 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL31151888 | 0.80 | ACHE (0.35) | FFAR1ALDH1A1MAPTHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024235121-A1 | FUSED RING COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-11-21 | — | — | WO | disclosed |