Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737319 | 1.00 | LMNA (0.49) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| SCHEMBL31152304 | 1.00 | LMNA (0.49) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL31152251 | 0.99 | LMNA (0.51) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL31152303 | 0.99 | LMNA (0.51) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL31152318 | 0.99 | LMNA (0.51) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| SCHEMBL31171517 | 0.88 | LMNA (0.47) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL31152316 | 0.87 | LMNA (0.49) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| SCHEMBL30873463 | 0.85 | LMNA (0.44) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| SCHEMBL29322135 | 0.85 | LMNA (0.44) | LMNAMAPTCYP2D6CYP1A2TSHR | |
| SCHEMBL27089386 | 0.85 | LMNA (0.44) | LMNAMAPTCYP2D6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259169-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-119119085-A | Substituted pyrimido ring inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024235225-A1 | SUBSTITUTED PYRIMIDINE-FUSED RING INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2024-11-21 | — | — | WO | disclosed |