Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334381 | 0.88 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL4700805 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL7951597 | 0.84 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL18263330 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL10994721 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL3108676 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL3233063 | 0.81 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL772349 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL16372262 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AGAACHRM2 | |
| SCHEMBL19908414 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AGAACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | ALDH1A1 3580/4885MEN1 1111/4885KMT2A 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.