Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819738 | 0.90 | TDP1 (0.51) | KMT2AUSP2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3127119 | 0.89 | ALDH1A1 (0.50) | KMT2AUSP2MAPK1ALDH1A1MEN1 | |
| SCHEMBL2819158 | 0.87 | KMT2A (0.50) | KMT2AUSP2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2819224 | 0.86 | KMT2A (0.47) | KMT2AUSP2ALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL2822895 | 0.86 | KMT2A (0.49) | KMT2AUSP2MAPK1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2825072 | 0.85 | KMT2A (0.47) | KMT2AUSP2ALDH1A1MEN1MAPT | |
| SCHEMBL2820050 | 0.85 | USP2 (0.64) | KMT2AUSP2ALDH1A1MEN1MAPT | |
| SCHEMBL2820130 | 0.82 | KMT2A (0.51) | KMT2AUSP2MAPK1ALDH1A1MEN1 | |
| SCHEMBL2820008 | 0.82 | KMT2A (0.51) | KMT2AUSP2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2823334 | 0.81 | USP2 (0.42) | KMT2AUSP2MAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700586-B2 | Arylsulfonamide derivatives for use as ccr3 antagonists in the treatment of inflammatory and immunological disorders | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-04-20 | — | — | US | claimed |