Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027277 | 0.86 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27870758 | 0.83 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27917300 | 0.83 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9375398 | 0.83 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27603435 | 0.83 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL14094466 | 0.81 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11064560 | 0.81 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6421933 | 0.80 | ADAMTS4 (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31220534 | 0.80 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6421929 | 0.80 | ADAMTS4 (0.68) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240353322-A1 | COMBINED DETERMINATION OF THE CONCENTRATION AND ENANTIOMERIC COMPOSITION OF CHIRAL COMPOUNDS USING SINGLE CHIROPTICAL ASSAY | GEORGETOWN UNIVERSITY | 2024-10-24 | — | — | US | disclosed |