Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 13/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857335 | 1.00 | MERTK (0.43) | MERTKMAPK8MAPK9HTTIRAK1 | |
| SCHEMBL22860693 | 0.90 | MERTK (0.46) | MERTKHTTJAK3MEN1GABBR2 | |
| SCHEMBL2622288 | 0.87 | GABBR2 (0.47) | MERTKHTTCDK2JAK3MEN1 | |
| SCHEMBL4713140 | 0.86 | GABBR2 (0.46) | MERTKHTTJAK3MEN1GABBR2 | |
| SCHEMBL4711841 | 0.86 | GABBR2 (0.46) | MERTKHTTJAK3MEN1GABBR2 | |
| SCHEMBL4715006 | 0.85 | MERTK (0.50) | MERTKHTTJAK3MEN1GABBR2 | |
| SCHEMBL19857398 | 0.82 | MAPK8 (0.45) | MERTKMAPK8MAPK9IRAK1CDK2 | |
| SCHEMBL29507857 | 0.81 | HTT (0.44) | MERTKHTTJAK3MEN1GABBR2 | |
| SCHEMBL24669666 | 0.81 | HTT (0.42) | MERTKMAPK8HTTIRAK1JAK1 | |
| SCHEMBL29507825 | 0.80 | MERTK (0.46) | MERTKHTTJAK3MEN1GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394966-B | Pyridopyrimidinone CDK2/4/6 inhibitors | 辉瑞公司 | 2024-10-11 | — | — | CN | disclosed |