Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785725 | 0.80 | MAPT (0.40) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL11015073 | 0.80 | MAPT (0.44) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL10913742 | 0.77 | KDM4E (0.41) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL30888682 | 0.77 | KDM4E (0.41) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL4779518 | 0.74 | HTR2A (0.41) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL10911503 | 0.74 | ATM (0.48) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL30888660 | 0.74 | HTR2A (0.41) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL10911885 | 0.73 | AR (0.52) | KDM4EMAPTGAAALDH1A1TP53 | |
| SCHEMBL31153456 | 0.72 | ALDH1A1 (0.42) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL23930147 | 0.72 | MAPT (0.35) | KDM4EMAPTGAAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |