Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31153544 | 0.94 | GPR35 (0.57) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL27373103 | 0.83 | GPR35 (0.67) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL25376725 | 0.81 | MAPT (0.46) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL31049739 | 0.81 | MAPT (0.46) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL15682730 | 0.80 | GPR35 (0.61) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL24150497 | 0.76 | GPR35 (0.59) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL25254905 | 0.75 | GPR35 (0.58) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL21865492 | 0.75 | GPR35 (0.58) | GPR35MAPTALDH1A1KMT2AGAA | |
| SCHEMBL4494650 | 0.75 | MAPT (0.45) | GPR35MAPTKMT2AGAAKDM4E | |
| SCHEMBL4493918 | 0.75 | MAPT (0.45) | GPR35MAPTKMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |