SCHEMBL31154476

SCHEMBL31154476

Nc1ccc(-c2ccc3ccc4cccnc4c3n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
MAPT P10636 5/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
TP53 P04637 3/20 0.55
LMNA P02545 3/20 0.55
CCR1 P32246 3/20 0.55
CCR5 P51681 3/20 0.55
CCR8 P51685 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
GMNN O75496 2/20 0.55
CYP3A4 P08684 2/20 0.55
THPO P40225 2/20 0.55
PMP22 Q01453 2/20 0.55
HSP90AA1 P07900 2/20 0.55
TSHR P16473 2/20 0.55
HTT P42858 2/20 0.55
MMP2 P08253 1/20 0.55
CYP2D6 P10635 1/20 0.55
MMP9 P14780 1/20 0.55
ALOX15 P16050 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12085758 1.00 KDM4E (0.55) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL599374 0.91 LMNA (0.67) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL29888960 0.89 LMNA (0.64) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL10032468 0.89 LMNA (0.64) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL20726724 0.88 LMNA (0.57) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL29192757 0.86 LMNA (0.59) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL30837267 0.86 LMNA (0.59) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL17146639 0.85 CCR1 (0.53) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL17174197 0.85 CCR1 (0.53) KDM4EMAPTSMN1; SMN2TP53LMNA
SCHEMBL17174041 0.84 LMNA (0.57) KDM4EMAPTSMN1; SMN2TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240352009-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2024-10-24 US disclosed
EP-4424682-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Hodogaya Chemical Co., Ltd. (JP) 2024-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240352009-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME EZH1, AZI2, EPCAM KDM4E 263/4885MAPT 1164/4885SMN1; SMN2 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.