Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232262 | 0.83 | SMARCA2 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL29232489 | 0.83 | SMARCA2 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL30163915 | 0.83 | SMARCA2 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL30163944 | 0.83 | SMARCA2 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL30163935 | 0.83 | SMARCA2 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL29232251 | 0.81 | GPR119 (0.46) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL30918491 | 0.80 | GPR119 (0.48) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL9963100 | 0.80 | GPR119 (0.48) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL9963102 | 0.80 | GPR119 (0.48) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL30774994 | 0.79 | GPR119 (0.47) | GPR119SMARCA2SMARCA4PBRM1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199402-A1 | HETEROCYCLIC COMPOUND AS AT2R ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118724877-A | Heterocyclic compounds as AT2R antagonists | 武汉人福创新药物研发中心有限公司 | 2024-10-01 | — | — | CN | disclosed |