Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808897 | 1.00 | CA2 (0.45) | CA2CA1NQO2NAMPTTDP1 | |
| SCHEMBL5117803 | 0.90 | CA1 (0.46) | CA2CA1NQO2NAMPTTDP1 | |
| SCHEMBL27377175 | 0.86 | GRM2 (0.45) | CA2CA1NAMPTGAACA12 | |
| SCHEMBL17823107 | 0.84 | CA1 (0.42) | CA2CA1NQO2NAMPTTDP1 | |
| SCHEMBL18041406 | 0.84 | KDM4E (0.46) | CA2CA1NQO2NAMPTTDP1 | |
| SCHEMBL23684240 | 0.83 | CNR1 (0.43) | CA2CA1NQO2NAMPTTDP1 | |
| SCHEMBL31156743 | 0.83 | CNR1 (0.46) | CA2CA1NQO2NAMPTPTGER4 | |
| SCHEMBL17823111 | 0.83 | CA1 (0.41) | CA2CA1NQO2NAMPTTDP1 | |
| SCHEMBL25808758 | 0.83 | CNR1 (0.46) | CA2CA1NQO2NAMPTPTGER4 | |
| SCHEMBL19026304 | 0.82 | CA1 (0.41) | CA2CA1NQO2NAMPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118829631-A | Pyrazine compounds as FLT3 inhibitors | 拜欧米富士恩公司 | 2024-10-22 | — | — | CN | disclosed |