Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31157573 | 0.91 | KDM4E (0.53) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL31157507 | 0.90 | PIK3CG (0.53) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL31157577 | 0.88 | PIK3CG (0.55) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL31157468 | 0.87 | PIK3CG (0.44) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| Hydrochloric Acid SCHEMBL31157444 | 0.85 | PIK3CG (0.50) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL9316471 | 0.79 | PIK3CG (0.65) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL31157594 | 0.79 | PIK3CG (0.45) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL31157523 | 0.77 | PIK3CG (0.45) | PIK3CGKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31157397 | 0.76 | PIK3CG (0.45) | PIK3CGKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL31157413 | 0.75 | CAPN1 (0.48) | PIK3CGKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376100-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | Redona Therapeutics, Inc. | 2024-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376100-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | PAPSS1, OTUD7B, BRD7 | PIK3CG 2909/4885KDM4E 2402/4885ALDH1A1 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.