SCHEMBL31157697

SCHEMBL31157697

CSCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIRT5 Q9NXA8 2/20 0.55
IL23R Q5VWK5 2/20 0.41
NPY4R P50391 7/20 0.41
NPY5R Q15761 6/20 0.41
NPY1R P25929 5/20 0.41
NPY2R P49146 3/20 0.41
FOLH1 Q04609 1/20 0.40
GNPAT O15228 1/20 0.40
TACR3 P29371 1/20 0.40
CCKBR P32239 1/20 0.39
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
PGGT1B P53609 1/20 0.39
CTSL P07711 1/20 0.39
CTSH P09668 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28645337 1.00 SIRT5 (0.55) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL28459707 1.00 SIRT5 (0.55) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL30120665 1.00 SIRT5 (0.55) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL31157760 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL30463256 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL30463278 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL12066140 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL31157647 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL30998021 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R
SCHEMBL30463260 0.97 SIRT5 (0.53) SIRT5IL23RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3548510-B1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MAT INC (US) 2024-10-02 EP disclosed