Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | NPY1R | P25929 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 2/20 | 0.40 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31157666 | 0.97 | BACE1 (0.45) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL29897725 | 0.97 | BACE1 (0.45) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL31157638 | 0.94 | SIRT5 (0.46) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL31157671 | 0.94 | SIRT5 (0.46) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL30463266 | 0.93 | GNPAT (0.53) | BACE1GNPATSIRT5IL23RFOLH1 | |
| SCHEMBL31157701 | 0.93 | BACE1 (0.45) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL31157720 | 0.93 | SIRT5 (0.46) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL31157700 | 0.93 | SIRT5 (0.46) | BACE1GNPATBACE2SIRT5NPY5R | |
| SCHEMBL3739792 | 0.92 | IL23R (0.45) | BACE1GNPATSIRT5NPY5RNPY1R | |
| SCHEMBL31157756 | 0.92 | IL23R (0.45) | BACE1GNPATSIRT5NPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548510-B1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MAT INC (US) | 2024-10-02 | — | — | EP | disclosed |