Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25579580 | 1.00 | BRD4 (0.48) | BRD4GPR119JAK2JAK1KDM4E | |
| SCHEMBL7389897 | 0.91 | BRD4 (0.48) | BRD4GPR119JAK2JAK1KDM4E | |
| SCHEMBL7389891 | 0.91 | BRD4 (0.48) | BRD4GPR119JAK2JAK1KDM4E | |
| SCHEMBL12635860 | 0.84 | KDM4E (0.56) | BRD4GPR119KDM4EPKML3MBTL1 | |
| SCHEMBL27187440 | 0.84 | BRD4 (0.47) | BRD4GPR119JAK2JAK1KDM4E | |
| SCHEMBL25241327 | 0.84 | HSD17B10 (0.49) | KDM4EHSD17B10L3MBTL1TP53 | |
| SCHEMBL30352385 | 0.84 | HSD17B10 (0.49) | KDM4EHSD17B10L3MBTL1TP53 | |
| SCHEMBL25579584 | 0.84 | KCNH2 (0.42) | BRD4GPR119JAK2JAK1KDM4E | |
| SCHEMBL21605864 | 0.83 | ACKR3 (0.51) | BRD4KDM4EPKMHSD17B10USP30 | |
| SCHEMBL23871348 | 0.83 | ACKR3 (0.51) | BRD4KDM4EPKMHSD17B10USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118804915-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2024-10-18 | — | — | CN | disclosed |