Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241327 | 1.00 | HSD17B10 (0.49) | HSD17B10MAPK1SMN1; SMN2MMP2MMP3 | |
| SCHEMBL25579580 | 0.84 | BRD4 (0.48) | HSD17B10TP53KDM4EL3MBTL1 | |
| SCHEMBL31157785 | 0.84 | BRD4 (0.48) | HSD17B10TP53KDM4EL3MBTL1 | |
| SCHEMBL23581880 | 0.77 | HSD17B10 (0.53) | HSD17B10MAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2883397 | 0.77 | HSD17B10 (0.53) | HSD17B10MAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15485406 | 0.76 | KMT2A (0.48) | HSD17B10MAPK1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL28665643 | 0.75 | KMT2A (0.45) | HSD17B10MAPK1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7389891 | 0.74 | BRD4 (0.48) | HSD17B10TP53KDM4EL3MBTL1 | |
| SCHEMBL7389897 | 0.74 | BRD4 (0.48) | HSD17B10TP53KDM4EL3MBTL1 | |
| SCHEMBL25223531 | 0.74 | PPIB (0.58) | HSD17B10MAPK1SMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429770-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086521-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2023-05-19 | — | — | WO | disclosed |