Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 9/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293468 | 1.00 | CSF1R (0.56) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL20598735 | 0.88 | NTRK1 (0.57) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL31157975 | 0.88 | CSF1R (0.56) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL30501448 | 0.88 | NTRK1 (0.57) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL23293521 | 0.88 | CSF1R (0.56) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL31000448 | 0.81 | CSF1R (0.55) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL20598490 | 0.81 | IRAK4 (0.59) | CSF1RPIM1PIM3IRAK4NTRK1 | |
| SCHEMBL20598482 | 0.80 | PIM1 (0.51) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL30501501 | 0.80 | PIM1 (0.51) | CSF1RPIM1PIM3IRAK4ALDH1A1 | |
| SCHEMBL17373830 | 0.78 | PIM1 (0.47) | PIM1PIM3IRAK4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118743770-A | Positron Emission Tomography (PET) radiotracer for imaging macrophage colony stimulating factor 1 receptor (CSF 1R) in neuroinflammation | 约翰霍普金斯大学 | 2024-10-08 | — | — | CN | disclosed |