SCHEMBL31158007

SCHEMBL31158007

CC(C)(C)OC(=O)N1CCC(c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C(F)(F)C1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 6/20 0.52
▸ DDB1 Q16531 1/20 0.52
▸ IKZF2 Q9UKS7 12/20 0.50
▸ CSNK1A1 P48729 2/20 0.49
▸ SALL4 Q9UJQ4 1/20 0.49
▸ IKZF1 Q13422 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31737012 1.00 CRBN (0.52) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL31736810 1.00 CRBN (0.52) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL21340261 0.91 CRBN (0.52) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL31157996 0.90 IKZF2 (0.56) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL20046085 0.87 IKZF2 (0.63) CRBNDDB1IKZF2IKZF1
SCHEMBL29583366 0.87 IKZF2 (0.63) CRBNDDB1IKZF2IKZF1
SCHEMBL28895861 0.86 CRBN (0.53) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL31091727 0.86 CRBN (0.54) CRBNDDB1SALL4
SCHEMBL31736792 0.85 IKZF2 (0.59) CRBNDDB1IKZF2IKZF1
SCHEMBL31736849 0.85 IKZF2 (0.59) CRBNDDB1IKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 — — WO disclosed
WO-2024233838-A1 METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) 2024-11-14 — — WO disclosed
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