SCHEMBL31736792

SCHEMBL31736792

CC(C)(C)OC(=O)N1CC[C@H](c2ccc3c(c2)CN([C@@H]2CCC(=O)NC2=O)C3=O)C1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IKZF2 Q9UKS7 17/20 0.59
IKZF1 Q13422 1/20 0.57
CRBN Q96SW2 2/20 0.54
DDB1 Q16531 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025879 1.00 IKZF2 (0.59) IKZF2IKZF1CRBNDDB1
SCHEMBL31737024 1.00 IKZF2 (0.59) IKZF2IKZF1CRBNDDB1
SCHEMBL31736849 1.00 IKZF2 (0.59) IKZF2IKZF1CRBNDDB1
SCHEMBL31736513 1.00 IKZF2 (0.59) IKZF2IKZF1CRBNDDB1
SCHEMBL29583366 0.95 IKZF2 (0.63) IKZF2IKZF1CRBNDDB1
SCHEMBL20046085 0.95 IKZF2 (0.63) IKZF2IKZF1CRBNDDB1
SCHEMBL24572309 0.94 IKZF2 (0.57) IKZF2IKZF1CRBNDDB1
SCHEMBL20765810 0.93 IKZF2 (0.60) IKZF2IKZF1CRBNDDB1
SCHEMBL29614672 0.92 IKZF2 (0.65) IKZF2IKZF1
SCHEMBL24421502 0.92 IKZF2 (0.65) IKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 WO disclosed