Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24570919 | 1.00 | SRD5A1 (0.44) | SRD5A1LMNAPKMKDM4ECCR5 | |
| SCHEMBL24570929 | 0.91 | SRD5A1 (0.42) | SRD5A1LMNAPKMKDM4ECCR5 | |
| SCHEMBL2571280 | 0.86 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2572769 | 0.86 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2571011 | 0.86 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL3866433 | 0.86 | CHRNA7 (0.46) | SRD5A1OPRM1OPRD1OPRK1CHRNA7 | |
| SCHEMBL31158036 | 0.84 | SRD5A1 (0.41) | SRD5A1 | |
| SCHEMBL31158043 | 0.84 | SRD5A1 (0.41) | SRD5A1OPRM1OPRD1OPRK1CHRNA7 | |
| SCHEMBL31158042 | 0.82 | SRD5A1 (0.42) | SRD5A1CCR5MTNR1B | |
| SCHEMBL13860426 | 0.82 | TAAR1 (0.43) | SRD5A1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745144-A | Novel EZH2 inhibitor compound, and preparation method and application thereof | 辽宁大学 | 2024-10-08 | — | — | CN | disclosed |