Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158034 | 0.91 | SRD5A1 (0.44) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL24570919 | 0.91 | SRD5A1 (0.44) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2572477 | 0.82 | SRD5A1 (0.40) | SRD5A1CCR5 | |
| SCHEMBL12039615 | 0.82 | SRD5A1 (0.40) | SRD5A1CCR5 | |
| SCHEMBL2572769 | 0.81 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2571011 | 0.81 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2571280 | 0.81 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL3866433 | 0.80 | CHRNA7 (0.46) | SRD5A1OPRM1OPRD1OPRK1 | |
| SCHEMBL31158032 | 0.80 | SRD5A1 (0.42) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL30584424 | 0.80 | NOTUM (0.42) | SRD5A1CCR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140555-A1 | CARBOXYLIC ACID CONTAINING INDANYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2022-06-30 | — | — | WO | disclosed |