SCHEMBL3115805

SCHEMBL3115805

C=C[SiH](C=C)c1cccc(CCCC)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.41
LIPG Q9Y5X9 3/20 0.41
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
SKP2 Q13309 1/20 0.38
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
XIAP P98170 1/20 0.37
HDAC4 P56524 1/20 0.36
MEF2D Q14814 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
PPARA Q07869 2/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293298 0.76 LPL (0.44) LPLLIPGSKP2NPC1HPGD
SCHEMBL347126 0.75 LPL (0.57) LPLLIPGSKP2NPC1HPGD
SCHEMBL12802506 0.74 LPL (0.45) LPLLIPGTHRATHRBSKP2
SCHEMBL12802006 0.74 TSHR (0.46) LPLLIPGTHRATHRBSKP2
SCHEMBL12802375 0.74 XIAP (0.46) LPLLIPGTHRATHRBSKP2
SCHEMBL30540423 0.74 TP53 (0.47) LPLLIPGTHRATHRBSKP2
SCHEMBL489025 0.74 TP53 (0.47) LPLLIPGTHRATHRBSKP2
SCHEMBL28409443 0.72 LPL (0.53) LPLLIPGSKP2NPC1HPGD
SCHEMBL28141752 0.72 LPL (0.63) LPLLIPGXIAPPPARAPPARG
SCHEMBL2918721 0.71 LPL (0.49) LPLLIPGSKP2NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10059788-B2 Organoaluminum activators on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-08-28 US claimed
US-20170313799-A1 Organoaluminum Activators on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2017-11-02 US claimed
US-10059788-B2 Organoaluminum activators on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-08-28 US disclosed
WO-2017189120-A1 ORGANOALUMINUM ACTIVATORS ON CLAYS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-11-02 WO disclosed
US-20170313799-A1 Organoaluminum Activators on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2017-11-02 US disclosed
US-7825202-B2 polybutadiene; butadiene-styrene copolymer; low to medium vinyl microstructure 10% to 40%; tire tread; improved wear and tear characteristics; potassium alkyl borohydride or potassium alkyl aluminum hydride; an organolithium compound; living lithium terminated; absence of polar modifiers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2010-11-02 US disclosed
US-20100093960-A1 Potassium Based Catalyst Systems For Synthesizing Rubbery Polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2010-04-15 US disclosed
US-7662883-B2 Rubbery block polymers containing polylactone and rubber compounds including the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 2010-02-16 US disclosed
US-7429549-B2 Process for improved coupling of rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-09-30 US disclosed
EP-1285932-B1 Barium metal containing catalyst system GOODYEAR TIRE & RUBBER (US) 2008-09-24 EP disclosed
EP-1967531-A1 Method of making alkoxy functionalized rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-09-10 EP disclosed
US-4845165-A ORGANOLITHIUM CATALYST; TIN TETRACHLORIDE BRANCHING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-07-04 US disclosed
CN-88101272-A POLYMERIZATION PROCESS 1988-11-09 CN disclosed
EP-0282437-A2 Polymerization process THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-09-14 EP disclosed
EP-0258167-A2 Modifier for lithium catalysts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-02 EP disclosed
US-4696986-A 1,2,3- OR 1,2,4-TRIALKOXYBENZENE MODIFIERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-29 US disclosed
US-4647634-A Randomizers for use in solution polymerizations THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-03-03 US disclosed
US-4525560-A PRODUCING HIGH LEVELS OF POLYMER SOLIDS WITHOUT REQUIRING COOLING,INCREMENTAL ADDITIONS, RECYCLING A PORTION OF TERMINATED POLYMER SMITH RICHARD L 1985-06-25 US disclosed
US-4137391-A Continuous solution polymerization of a conjugated diene with a monovinylaromatic compound using alkoxysilicon treating agents in the first reactor means of a reactor series PHILLIPS PETROLEUM COMPANY (US) 1979-01-30 US disclosed
US-4091198-A Suppressing gel in the continuous solution polymerization of a conjugated diene with a monovinyl aromatic compound PHILLIPS PETROLEUM COMPANY (US) 1978-05-23 US disclosed