Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.49 |
| ▸ | PPARA | Q07869 | 9/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.43 |
| ▸ | PTGES | O14684 | 7/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094832 | 0.85 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL6092845 | 0.85 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL3100619 | 0.80 | PPARA (0.71) | PPARGPPARAPPARD | |
| SCHEMBL3946198 | 0.80 | PPARA (0.71) | PPARGPPARAPPARD | |
| SCHEMBL3100628 | 0.80 | PPARA (0.71) | PPARGPPARAPPARD | |
| SCHEMBL5474463 | 0.80 | PPARA (0.70) | PPARGPPARAPPARD | |
| SCHEMBL13156113 | 0.77 | PPARA (0.60) | PPARGPPARAPPARD | |
| SCHEMBL5689292 | 0.76 | PPARA (0.63) | PPARGPPARAALOX5PTGESPPARD | |
| Tert-Butylamine SCHEMBL3112027 | 0.76 | PPARA (0.68) | PPARGPPARAPPARD | |
| Piperazine SCHEMBL5413975 | 0.76 | PPARA (0.65) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803586-B2 | Chemical Process | ASTRAZENECA AB (SE) | 2010-09-28 | — | — | US | disclosed |