Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081094 | 0.78 | PBRM1 (0.49) | PBRM1SMARCA2SMARCA4TNKS2CA1 | |
| SCHEMBL23089566 | 0.78 | PBRM1 (0.49) | PBRM1SMARCA2SMARCA4TNKS2TSHR | |
| SCHEMBL29872293 | 0.77 | PBRM1 (0.46) | PBRM1SMARCA2SMARCA4TNKS2ROCK2 | |
| SCHEMBL31159197 | 0.74 | PBRM1 (0.44) | PBRM1SMARCA2SMARCA4TNKS2ROCK2 | |
| SCHEMBL18497872 | 0.71 | PBRM1 (0.38) | PBRM1SMARCA2SMARCA4TNKS2CA1 | |
| SCHEMBL30566043 | 0.68 | SMARCA2 (0.41) | PBRM1SMARCA2SMARCA4TNKS2CA1 | |
| SCHEMBL8293271 | 0.68 | TSHR (0.48) | PBRM1TNKS2TSHRMEN1KMT2A | |
| SCHEMBL19573959 | 0.68 | TNKS2 (0.49) | PBRM1TNKS2TSHRKMT2A | |
| SCHEMBL19573960 | 0.68 | TNKS2 (0.49) | PBRM1TNKS2TSHRKMT2A | |
| SCHEMBL31667419 | 0.68 | TNKS2 (0.49) | PBRM1TNKS2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |