Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159517 | 0.89 | MAPT (0.55) | SMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL31159510 | 0.88 | ALDH1A1 (0.65) | KMT2AMAPTALDH1A1 | |
| SCHEMBL31159569 | 0.88 | KMT2A (0.64) | KMT2AMAPTALDH1A1 | |
| SCHEMBL31159502 | 0.86 | NPSR1 (0.65) | KMT2AMAPTALDH1A1 | |
| SCHEMBL31159556 | 0.86 | GSK3B (0.62) | KMT2AMAPTALDH1A1 | |
| SCHEMBL31159568 | 0.83 | MAPT (0.59) | SMN1; SMN2KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL31159591 | 0.81 | MAPT (0.66) | SMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL31159567 | 0.80 | MAPT (0.58) | MAPTALDH1A1 | |
| SCHEMBL31159548 | 0.77 | ALDH1A1 (0.67) | MAPTTP53ALDH1A1 | |
| SCHEMBL31159545 | 0.75 | KMT2A (0.69) | KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496218-A | Carbazole-oxadiazole alpha-glucosidase and alpha-amylase double-target inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-08-16 | — | — | CN | disclosed |