SCHEMBL31159751

SCHEMBL31159751

N#Cc1ccc(COc2c(F)cccc2C2CCNCC2)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 13/20 0.61
SLC6A4 P31645 13/20 0.61
SLC6A3 Q01959 10/20 0.61
HTR1A P08908 10/20 0.61
HTR6 P50406 6/20 0.48
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25971055 0.85 SLC6A2 (0.70) SLC6A2SLC6A4SLC6A3HTR1AHTR6
SCHEMBL24574655 0.83 HTR6 (0.56) SLC6A2SLC6A4SLC6A3HTR1AHTR6
SCHEMBL24919613 0.80 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3HTR1AHTR6
SCHEMBL20280066 0.78 GLP1R (0.52) HTR1A
SCHEMBL29518203 0.78 GLP1R (0.52) HTR1A
SCHEMBL30899099 0.78 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3HTR1AHTR6
Hydrochloric Acid SCHEMBL28781153 0.78 GLP1R (0.51) HTR1A
Hydrochloric Acid SCHEMBL29664360 0.78 GLP1R (0.51) HTR1A
SCHEMBL3321425 0.77 SLC6A2 (0.70) SLC6A2SLC6A4SLC6A3HTR1AHTR6
SCHEMBL31140532 0.76 PRMT5 (0.46) SLC6A2SLC6A4SLC6A3HTR1AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688144-A1 COMPOUNDS AS GLP-1R AGONISTS Terns Pharmaceuticals, Inc. (US) 2026-02-11 EP disclosed
WO-2024206878-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. (US) 2024-10-03 WO disclosed