SCHEMBL31159797

SCHEMBL31159797

C[C@@]1(c2ccc(Cl)cn2)C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.33
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779905 1.00 PTK2 (0.33) PTK2ADRA2AADRA2BADRA2CL3MBTL1
SCHEMBL17382631 0.82 CCR1 (0.35) ADRA2AADRA2BADRA2C
SCHEMBL29777956 0.75 SLC6A2 (0.36)
SCHEMBL22911623 0.75 SLC6A2 (0.36)
SCHEMBL30217567 0.74 MAPK1 (0.34)
SCHEMBL30431565 0.74 TRPA1 (0.33)
SCHEMBL30431794 0.71 TRPA1 (0.31)
SCHEMBL30431942 0.71 TRPA1 (0.31)
SCHEMBL30432144 0.71 TRPA1 (0.31)
SCHEMBL24442230 0.70 PTK2 (0.39) PTK2ADRA2AADRA2BADRA2CL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688144-A1 COMPOUNDS AS GLP-1R AGONISTS Terns Pharmaceuticals, Inc. (US) 2026-02-11 EP disclosed
WO-2024206878-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. (US) 2024-10-03 WO disclosed