Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27255559 | 0.83 | KDM4E (0.45) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL10683847 | 0.82 | KDM4E (0.53) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL31160023 | 0.77 | SMN1; SMN2 (0.50) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL30418756 | 0.77 | KDM4E (0.53) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL18031417 | 0.77 | KDM4E (0.53) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL23905892 | 0.76 | CNR2 (0.49) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL26579774 | 0.76 | KDM4E (0.58) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL1457837 | 0.76 | CA12 (0.46) | KDM4EPOLBMAPTLMNACNR2 | |
| SCHEMBL25351231 | 0.75 | HDAC1 (0.55) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL31160000 | 0.74 | MAPT (0.40) | KDM4EMAPTLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688144-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206878-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |