Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1457837 | 0.84 | CA12 (0.46) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL31160123 | 0.80 | MAPT (0.41) | MAPTALDH1A1GAAHTTHSD17B10 | |
| SCHEMBL31160045 | 0.75 | CA12 (0.45) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL31159824 | 0.74 | KDM4E (0.42) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7928469 | 0.74 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5218033 | 0.73 | HCAR3 (0.52) | MAPTALDH1A1KDM4EHTTLMNA | |
| SCHEMBL31160054 | 0.72 | MAPT (0.43) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27255559 | 0.72 | KDM4E (0.45) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL31463453 | 0.72 | KMT2A (0.37) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL31463454 | 0.72 | KMT2A (0.37) | MAPTALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688144-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206878-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |