SCHEMBL31160503

SCHEMBL31160503

COc1ccc(/C(=C\C(=O)O)C(=O)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
AKR1C3 P42330 1/20 0.54
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
PARP1 P09874 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 1/20 0.49
ATM Q13315 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
PLK1 P53350 1/20 0.47
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5645079 0.86 CA1 (0.53) CA1CA2CES2CES1PARP1
SCHEMBL8895115 0.85 CA1 (0.61) CA1CA2AKR1C3CES2CES1
SCHEMBL4775774 0.83 CA1 (0.59) CA1CA2AKR1C3CES2CES1
SCHEMBL4775778 0.83 CA1 (0.59) CA1CA2AKR1C3CES2CES1
SCHEMBL7074876 0.81 CA1 (0.57) CA1CA2CES2CES1PARP1
SCHEMBL10722665 0.81 CA1 (0.57) CA1CA2AKR1C3CES2CES1
SCHEMBL9220935 0.81 CA1 (0.57) CA1CA2AKR1C3CES2CES1
SCHEMBL9220929 0.81 CA1 (0.57) CA1CA2AKR1C3CES2CES1
SCHEMBL29241975 0.81 CA1 (0.57) CA1CA2AKR1C3CES2CES1
SCHEMBL17200993 0.81 CA1 (0.61) CA1CA2CES2CES1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019389-B 7-Azaindole compound and synthetic method and application thereof SICHUAN UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-119019389-A 7-Azaindole compound and synthetic method and application thereof 四川大学 2024-11-26 CN disclosed