SCHEMBL5645079

SCHEMBL5645079

COC(=O)C(=CC(=O)O)c1ccc(OC)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.53
CA2 P00918 6/20 0.53
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49
PLK1 P53350 1/20 0.49
RAB9A P51151 2/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PARP1 P09874 1/20 0.47
PARP10 Q53GL7 1/20 0.47
PARP2 Q9UGN5 1/20 0.47
PARP4 Q9UKK3 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77602 0.86 CA1 (0.52) CA1CA2CES2CES1ALDH1A1
SCHEMBL2516538 0.86 CA1 (0.52) CA1CA2CES2CES1ALDH1A1
SCHEMBL6389400 0.86 CA1 (0.52) CA1CA2CES2CES1ALDH1A1
SCHEMBL31160503 0.86 CA1 (0.57) CA1CA2CES2CES1ALDH1A1
SCHEMBL1983412 0.84 ALDH1A1 (0.60) CES2CES1ALDH1A1RAB9AHPGD
SCHEMBL6389410 0.84 ALDH1A1 (0.51) CA1CA2CES2CES1ALDH1A1
SCHEMBL4007049 0.84 TSHR (0.50) CES2CES1ALDH1A1RAB9AMAPK1
SCHEMBL4007052 0.84 TSHR (0.50) CES2CES1ALDH1A1RAB9AMAPK1
Methane SCHEMBL534895 0.82 TSHR (0.48) CA1CES2CES1ALDH1A1RAB9A
SCHEMBL671800 0.80 HTT (0.51) ALDH1A1CYP3A4RAB9AMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461396-B Additive composition and use thereof, condensation polymer composition, molding compound prepared from same and molded part and use thereof 弗劳恩霍夫应用研究促进协会 2024-07-12 CN disclosed
CN-118234793-A Stabilizer based on syringic acid, vanillic acid, isovanillic acid or 5-hydroxyveratric acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-06-21 CN disclosed
CN-118165743-A Polymerizable oligomeric liquid crystals, polymerizable medium and polymerized liquid crystal films 默克专利股份有限公司 2024-06-11 CN disclosed
CN-117715965-A Improved polymer compositions 杜邦聚合物公司 2024-03-15 CN disclosed
CN-114616264-B Oligomer or polymer, composition, use of oligomer or polymer and intermediate 弗劳恩霍夫应用研究促进协会 2024-03-01 CN disclosed
EP-4314141-A1 STABILIZER MIXTURE BASF SE (DE) 2024-02-07 EP disclosed
CN-117511196-A Flame retardant polyamide composition 科莱恩国际有限公司 2024-02-06 CN disclosed
CN-110997872-B Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2024-01-02 CN disclosed
CN-117280011-A Reactive mesogen 默克专利股份有限公司 2023-12-22 CN disclosed
CN-117222700-A Use of a stabilizer composition for stabilizing organic materials, stabilizer composition, masterbatch, composition, molding compound for molded parts, method for oxidative stabilization, thermal stabilization, photochemical stabilization of thermoplastics, and use of a composition 弗劳恩霍夫应用研究促进协会 2023-12-12 CN disclosed
EP-0665258-B1 Piperidenyle compounds and their use as a photostabilizer for polymers RHODIA CHIMIE SA (FR) 1998-07-01 EP disclosed
EP-0388321-B1 Piperidinyle compounds and their use as a photostabilizer for polymers RHONE POULENC CHIMIE (FR) 1996-12-18 EP disclosed
EP-0665258-A2 Piperidenyle compounds and their use as a photostabilizer for polymers RHONE-POULENC CHIMIE (FR) 1995-08-02 EP disclosed
US-5356967-A Raeacting formed Grignard reagent with a chloro-dibenzooxa-phosphorine derivative HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
US-5298541-A Molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
EP-0365469-B1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA GEIGY AG (CH) 1994-02-02 EP disclosed
US-5281640-A For thermoplastic or thermosetting plastics, polymer-containing polymerized mono- or diolefin molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-25 US disclosed
EP-0214507-B1 OUTDOOR FILMS STABILIZED AGAINST CHEMICAL ATTACK AMERICAN CYANAMID COMPANY (US) 1992-01-15 EP disclosed
EP-0388321-A1 Piperidinyle compounds and their use as a photostabilizer for polymers RHONE-POULENC CHIMIE (FR) 1990-09-19 EP disclosed
EP-0365469-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed