Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.57 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.52 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22536049 | 1.00 | CRBN (0.57) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| SCHEMBL29641124 | 1.00 | CRBN (0.57) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| SCHEMBL29596179 | 1.00 | CRBN (0.57) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| SCHEMBL20046182 | 1.00 | CRBN (0.57) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| Hydrochloric Acid SCHEMBL22581068 | 0.99 | CRBN (0.56) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| SCHEMBL20046597 | 0.96 | CRBN (0.57) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| Trifluoroacetic Acid SCHEMBL30939002 | 0.92 | IKZF2 (0.51) | CRBNIKZF2IKZF1CSNK1A1DDB1 | |
| SCHEMBL25328847 | 0.90 | CRBN (0.58) | CRBNIKZF2IKZF1CSNK1A1DRD2 | |
| SCHEMBL24717747 | 0.90 | IKZF2 (0.50) | CRBNIKZF2IKZF1DRD2ADRA1D | |
| SCHEMBL30720935 | 0.90 | IKZF2 (0.50) | CRBNIKZF2IKZF1DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673449-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | Differentiated Therapeutics Inc (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182555-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |