Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 9/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539245 | 0.91 | DDB1 (0.50) | DDB1CRBNBRD4SOS1 | |
| SCHEMBL29977165 | 0.86 | DDB1 (0.53) | DDB1CRBNBRD4JAK1SOS1 | |
| SCHEMBL23538393 | 0.86 | DDB1 (0.53) | DDB1CRBNBRD4JAK1SOS1 | |
| SCHEMBL29977269 | 0.82 | CRBN (0.52) | DDB1CRBNBRD4 | |
| SCHEMBL31433980 | 0.79 | DDB1 (0.45) | DDB1CRBNBRD4JAK1SOS1 | |
| SCHEMBL31160824 | 0.79 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL30990634 | 0.78 | DDB1 (0.50) | DDB1CRBNBRD4JAK1 | |
| SCHEMBL23539369 | 0.78 | CRBN (0.50) | DDB1CRBNBRD4JAK1SOS1 | |
| SCHEMBL23539064 | 0.78 | DDB1 (0.52) | DDB1CRBNBRD4JAK1 | |
| SCHEMBL29147434 | 0.78 | DDB1 (0.53) | DDB1CRBNBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062426-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4673449-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | Differentiated Therapeutics Inc (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182555-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062426-A1 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | CCNA1, CCNE1, CCNA2 | DDB1 308/4885CRBN 429/4885BRD4 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.