Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312670 | 0.92 | HPGD (0.42) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL312841 | 0.88 | AKR1B1 (0.50) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL312223 | 0.88 | AKR1B1 (0.56) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL313038 | 0.86 | HPGD (0.46) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL312060 | 0.86 | HPGD (0.44) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL311784 | 0.86 | AKR1B1 (0.46) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL311791 | 0.86 | HPGD (0.51) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL311364 | 0.84 | HPGD (0.44) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL324201 | 0.84 | HPGD (0.61) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL312485 | 0.83 | HPGD (0.39) | AKR1B1HPGDKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |