Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 6/20 | 0.42 |
| ▸ | EIF2AK3 | Q9NZJ5 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311578 | 0.92 | HPGD (0.45) | HPGDKDM4EHSD17B10LMNABRAF | |
| SCHEMBL311364 | 0.89 | HPGD (0.44) | HPGDKDM4EHSD17B10LMNABRAF | |
| SCHEMBL311129 | 0.85 | HPGD (0.63) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL311739 | 0.85 | KDM4E (0.44) | HPGDKDM4EHSD17B10LMNABRAF | |
| SCHEMBL312315 | 0.82 | HPGD (0.38) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL312060 | 0.81 | HPGD (0.44) | HPGDKDM4EHSD17B10LMNABRAF | |
| SCHEMBL312665 | 0.80 | MAOB (0.45) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL311550 | 0.80 | HPGD (0.38) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL312404 | 0.80 | HPGD (0.45) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL311722 | 0.78 | ALDH1A1 (0.38) | HPGDKDM4EHSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |