Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122686 | 0.90 | HDAC1 (0.48) | HDAC1MEN1KMT2A | |
| SCHEMBL3114908 | 0.88 | HDAC1 (0.43) | HDAC1MEN1KMT2AGCGR | |
| SCHEMBL3112440 | 0.84 | MEN1 (0.50) | HDAC1MEN1KMT2A | |
| SCHEMBL27799425 | 0.84 | HDAC1 (0.52) | HDAC1MEN1KMT2A | |
| SCHEMBL3119589 | 0.83 | MEN1 (0.50) | HDAC1MEN1KMT2A | |
| SCHEMBL3112748 | 0.82 | GCGR (0.42) | HDAC1MEN1KMT2AGCGR | |
| SCHEMBL3108456 | 0.81 | MEN1 (0.48) | HDAC1MEN1KMT2A | |
| SCHEMBL3119810 | 0.81 | MEN1 (0.50) | HDAC1MEN1KMT2A | |
| SCHEMBL3108392 | 0.80 | MET (0.47) | HDAC1MEN1KMT2A | |
| SCHEMBL13247316 | 0.80 | MET (0.64) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367668-B2 | Pyridazinone derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20100179148-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179148-A1 | PYRIDAZINONE DERIVATIVES | MET, ERBB2, RET | HDAC1 1192/4885MEN1 121/4885KMT2A 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.